Detail
Basic information
Chemical name: 4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]benzonitrile
MF: C14H10BNO3
MW: 251.05
Physical & Chemical Properties
Form powder
Color white to beige
Melting point >130°C (softened)
Boiling point 425.9±55.0 °C(Predicted)
Density 1.33±0.1 g/cm3(Predicted)
Storage temp. room temp
Solubility DMSO (Slightly), Methanol (Slightly)
pka 7.00±0.20(Predicted)
Stability: Hygroscopic
Usage / Application
A series of phenoxy benzoxaboroles were synthesized and screened for their inhibitory activity against PDE4 and cytokine release. 5-(4-Cyanophenoxy)-2,3-dihydro-1-hydroxy-2,1-benzoxaborole (AN2728) showed potent activity both in vitro and in vivo. AN2728 is being studied as an anti-inflammatory agent.
Specifications:98%
Use:
